KAT6A/YAP/TEAD4 pathway modulates osteoclastogenesis by regulating the RANKL/OPG ratio on the compression side during orthodontic tooth movement
Abstract Background Orthodontic tooth movement (OTM) is a dynamic equilibrium of bone remodeling, involving the osteogenesis of new bone and the osteoclastogenesis of old bone, which is mediated by mechanical force.Periodontal ligament stem cells (PDLCSs) in the periodontal ligament (PDL) space can Bath Bomb transmit mechanical signals and regulate